The GenoCare 1600 Single Molecule Sequencer successfully passed the registration test of CFDA.
The single-molecule sequencer GenoCare 27# was sent to Shenzhen Luohu People's Hospital and became the first sequencer product to be delivered to users.
Moved to the new site, settled in the Shenye Jinyuan Building in Luohu District, with a total office and R&D area of more than 5,000 square meters.
The first application of single-molecule sequencing in preimplantation genetic screening (PGS). The results of micro-cell sequencing showed that single-molecule sequencing does not require PCR amplification, and is significantly better than second-generation sequencing in terms of sample processing time, GC preference, and data volatility.
Achieve full self-production of enzymes for single molecule sequencing.
Get a total of 218 million yuan of A round of financing, which was jointly participated by five institutions, focused on the construction of the third-generation genetic sequencer and supporting reagent production lines and the declaration of medical device licenses.
The GMP standard kit production line with an area of more than 2,000 square meters was officially completed, and reagents and chips began to start trial production.
Completed the “non-invasive prenatal testing research based on the third-generation gene sequencer”, which is the first case in China to use the single-molecule sequencing technology for clinical detection of NIPT. NIPT test results showed that the positive and positive coincidence rates reached 100%, and the GC preference was significantly lower than that of the second-generation sequencer.
CCTV welcomed the 19th special program "Looking at the Present", focusing on the company and the third-generation gene sequencer GenoCare.
Published sequencing data on BioRxiv.
The third-generation gene sequencer major results conference was held in Shenzhen, and the single-molecule sequencer GenoCare was officially announced.
Released Beta versions of GenoCare?.
Achieve full self-synthesis production of single molecule sequencing core reagents.
Resequencing the Escherichia coli genome by GenoCare single molecule sequencing platform.
For the first time, single-molecule sequencing of biological samples was achieved, and the results of sequencing data were released.
The results of single-molecule targeted sequencing based on the GenoCare principle prototype were officially published in the international academic journal Scientific Reports.
Engineering prototype of GenoCare?.
Realizing the independent research and development of TIRF microscopic imaging system for the first time.
Nature Biotechnology Journal Reports on GenoCare System.
Release first prototype – GenoCare? analyzer.
Automated single-molecule sequencing process for the first time, end the era of manual sequencing.
First achieving single-molecular targeted sequencing.
First achieving single-molecular image capture.
Received seed funding from Amer International Group.
Direct Genomics was founded at Shenzhen， China.